The Molecular Information Systems Lab (MISL) at the University of Washington explores the intersection of information technology and molecular-level manipulation using in-silico and wet lab experiments. A partnership between UW 小火箭节点二维码分享, 小火箭免费节点公众号, and Microsoft Research, MISL brings together faculty, students and research scientists with expertise in computer architecture, programming languages, synthetic biology, and biochemistry.
Our current focus is on using synthetic DNA for data storage. Using DNA to archive data is an attractive possibility because it is extremely dense, with a raw limit of 1 exabyte per cubic milimeter, and long-lasting, with observed half-life of over 500 years. We are developing a complete system architecture for DNA-backed archival storage, with support for random access and encoding schemes that offer reliability for density trade-offs.
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Our latest paper is out! Reading and writing in DNA data storage involves synthesizing and manipulating large pools of DNA molecules with (often) uneven distribution. We go deep on that in this paper!
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Karin and Luis have earned the ACM SIGARCH Maurice Wilkes Award for their career contributions to DNA-based digital data storage! Congrats Karin and Luis!
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May 28, 2023
Our latest preprint showcases our technique for augmenting DNA data storage with the ability to perform similarity search over a database with millions of images!
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Katie was interviewed for a podcast about Porcupine – Bioinformatics Chat by Roman Cheplyaka. The episode should be out by the end of the month!
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March 30, 2023
Congratulations to Karen Zhang for the Goldwater Scholarship and David Wong for the Mary Gates Scholarship! Woo!
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March 08, 2023
Check out our latest preprint on Porcupine, a molecular tagging system using DNA to tag physical objects and basecall-free nanopore signals for reading!
Older posts…
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Nanopore Sensing
We are exploring new and non-traditional ways to use nanopore technology for bespoke molecular sensing, synthetic biology and proteomics.
DNA Circuits
We are exploring new approaches to build complex DNA circuits by using automatic microfluidic hardware and array-based DNA synthesis technology.
DNA Storage Architecture and Methods
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Microfluidic Automation
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DNA Security
We are exploring the intersection of DNA manipulation and security and privacy.
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Luis Ceze
Karin Strauss
Affiliate Professor
Georg Seelig
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Chris Takahashi
Jeff Nivala
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Max Willsey
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Katie Doroschak
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Peter Ney
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Aishwarya Mandyam
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Philip Leung
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Rob Carlson
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